COMP Protein (His tag)

N° du produit ABIN2567001

Détail du produit

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette COMP protéine est marqué à la His tag.

Application: Western Blotting (WB)

Attributs du produit:

Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells, when rhCOMP / Thrombospondin-5 immobilized at 1 μg/well. More than 45 % of ATDC-5 cell adhesion will be induced.

Pureté: >88 % as determined by SDS-PAGE.

Information d'application

Indications d'application: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -80 °C,-20 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Autre désignation: TSP5 (COMP Produits)

Synonymes: COMP Protein, EDM1 Protein, EPD1 Protein, MED Protein, PSACH Protein, THBS5 Protein, TSP5 Protein, cartilage oligomeric matrix protein Protein, COMP Protein, sce3551 Protein, CJA_1292 Protein, Comp Protein

Sujet: Cartilage oligomeric matrix protein (COMP) is also known as Thrombospondin-5 (TSP5), EDM1, EPD1, MED, PSACH, THBS5, which belongs to the thrombospondin family. COMP / TSP5 contains 4 EGF-like domains, 1 TSP C-terminal (TSPC) domain, 8 TSP type-3 repeats. Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. COMP may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. COMP can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Thrombospondin-5 could play a role in the pathogenesis of osteoarthritis. COMP is a marker of cartilage turnover.

Poids moléculaire: 82 kDa

ID gène: 1311

UniProt: P49747