BRD9 Protein (AA 130-259) (His tag,DYKDDDDK Tag)

N° du produit ABIN2669647

Détail du produit

Antigène: BRD9 (Bromodomain Containing 9 (BRD9))

Type de proteíne: Recombinant

Attributs du protein: AA 130-259

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BRD9 protéine est marqué à la His tag,DYKDDDDK Tag.

Application: Binding Studies (Bind), Screening Assay (ScA)

Attributs du produit: The peptide corresponding to amino acids 130 - 259 that contains the bromodomain sequences of BRD9 (accession number NM_023924.4) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.9 kDa.

Information d'application

Indications d'application: Recombinant BRD9 (130-259) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Détail du antigène

Antigène: BRD9 (Bromodomain Containing 9 (BRD9))

Autre désignation: BRD9 (BRD9 Produits)

Synonymes: LAVS3040 Protein, PRO9856 Protein, AL022779 Protein, zgc:55797 Protein, BRD9 Protein, bromodomain containing 9 Protein, bromodomain containing 9 L homeolog Protein, BRD9 Protein, Brd9 Protein, brd9 Protein, brd9.L Protein

Sujet: Bromodomain-containing protein 9 (BRD9) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6) that function in the regulation of transcriptional activation and chromatin remodeling. There are five isoforms of BRD9 that are produced by alternative splicing.

Poids moléculaire: 20.9 kDa