Polybromo 1 Protein (PBRM1) (AA 613-734) (His tag,DYKDDDDK Tag)
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- Antigène Voir toutes Polybromo 1 (PBRM1) Protéines
- Polybromo 1 (PBRM1)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 613-734
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Polybromo 1 protéine est marqué à la His tag,DYKDDDDK Tag.
- Attributs du produit
- The peptide corresponding to amino acids 613 - 734 that contains the bromodomain sequences of PBRM1 (accession number NP_060635.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 20.513 kDa. It shows binding specificity for acetylated H3K14.
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- Discover our top product PBRM1 Protéine
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Polybromo 1 (PBRM1) (AA 53-345) protein (His tag)
PBRM1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Polybromo 1 (PBRM1) (AA 1-306) protein (GST tag)PBRM1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Polybromo 1 (PBRM1) (AA 1-1634) protein (Strep Tag)Crystallography grade PBRM1 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Stock
- -80 °C
- Stockage commentaire
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.
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- Antigène
- Polybromo 1 (PBRM1)
- Autre désignation
- PBRM1 (PBRM1 Produits)
- Synonymes
- pb1 Protein, BAF180 Protein, PB1 Protein, 2610016F04Rik Protein, AI507524 Protein, Pb1 Protein, RGD1565549 Protein, polybromo 1 Protein, polybromo 1 L homeolog Protein, protein polybromo-1 Protein, PBRM1 Protein, pbrm1.L Protein, LOC100170602 Protein, pbrm1 Protein, Pbrm1 Protein
- Sujet
- Polybromo 1 (PBRM1) protein, also known as BRG1-associated factor 180 (BAF180) is the chromatin targeting subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex that is involved in transcriptional activation and repression of select genes. PBRM1 targets chromatin via its six bromodomains that recognize and bind acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. PBRM1 also acts as an inhibitor of cell proliferation and demonstrates tumor suppressing properties in relation to breast, liver and lung cancers.
- Poids moléculaire
- 20.513 kDa
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