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Collagen Type IX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2712425
  • Antigène Tous les produits Collagen Type IX
    Collagen Type IX
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    Humain
    Source
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Collagen Type IX protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Collagen type IX (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    Collagen Type IX
    Abstract
    Collagen Type IX Produits
    Sujet
    This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
    Poids moléculaire
    62 kDa
    NCBI Accession
    NP_511040
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