Claudin 19 Protein (CLDN19) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712853

Détail du produit

Antigène: Claudin 19 (CLDN19)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Claudin 19 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Claudin-19 / CLDN19 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Claudin 19 (CLDN19)

Autre désignation: Claudin-19,cldn19 (CLDN19 Produits)

Synonymes: HOMG5 Protein, claudin-19 Protein, zgc:112141 Protein, claudin 19 Protein, claudin 19 S homeolog Protein, CLDN19 Protein, Cldn19 Protein, cldn19.S Protein, cldn19 Protein

Sujet: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 23 kDa

NCBI Accession: NP_683763

Pathways: Cell-Cell Junction Organization, Hepatitis C