CLN6 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2712884

Détail du produit

Antigène: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CLN6 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CLN6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CLN6 (Ceroid-Lipofuscinosis, Neuronal 6, Late Infantile, Variant (CLN6))

Autre désignation: Cln6 (CLN6 Produits)

Synonymes: 1810065L06Rik Protein, AW743417 Protein, D9Bwg1455e Protein, nclf Protein, CLN4A Protein, HsT18960 Protein, cln6 Protein, zgc:103565 Protein, ceroid-lipofuscinosis, neuronal 6 Protein, CLN6, transmembrane ER protein Protein, CLN6, transmembrane ER protein S homeolog Protein, ceroid-lipofuscinosis, neuronal 6, late infantile, variant Protein, CLN6, transmembrane ER protein a Protein, Cln6 Protein, CLN6 Protein, cln6.S Protein, cln6a Protein

Sujet: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Poids moléculaire: 35.7 kDa

NCBI Accession: NP_060352

Pathways: Glycosaminoglycan Metabolic Process