CTSC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713232

Détail du produit

Antigène: CTSC (Cathepsin C (CTSC))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CTSC protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Cathepsin C (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: Cathepsin C (CTSC Produits)

Synonymes: CPPI Protein, DPP-I Protein, DPP1 Protein, DPPI Protein, HMS Protein, JP Protein, JPD Protein, PALS Protein, PDON1 Protein, PLS Protein, MGC69126 Protein, MGC107782 Protein, AI047818 Protein, CATC Protein, cb912 Protein, ik:tdsubc_1h2 Protein, sb:cb146 Protein, wu:fb34g12 Protein, wu:fj58d01 Protein, cathepsin C Protein, cathepsin C L homeolog Protein, cathepsin CPC1 Protein, CTSC Protein, ctsc.L Protein, ctsc Protein, TP03_0357 Protein, CMU_003360 Protein, CPC1 Protein, NAEGRDRAFT_80477 Protein, NAEGRDRAFT_37577 Protein, Ctsc Protein, Smp_183330 Protein

Sujet: This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Poids moléculaire: 49.5 kDa

NCBI Accession: NP_001805