CENPM Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713909

Détail du produit

Antigène: CENPM (Centromere Protein M (CENPM))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CENPM protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CENP-M (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CENPM (Centromere Protein M (CENPM))

Autre désignation: Cenp-M (CENPM Produits)

Synonymes: C22orf18 Protein, CENP-M Protein, PANE1 Protein, bK250D10.2 Protein, 2610019I03Rik Protein, AI853711 Protein, Pane1 Protein, RGD1307309 Protein, centromere protein M Protein, centromere protein M L homeolog Protein, Centromere protein M Protein, centromere protein M pseudogene Protein, CENPM Protein, Cenpm Protein, cenpm Protein, cenpm.L Protein, LOC100353362 Protein

Sujet: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 19.6 kDa

NCBI Accession: NP_076958