CHFR Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713969

Détail du produit

Antigène: CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CHFR protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CHFR / RNF196 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CHFR (Checkpoint with Forkhead and Ring Finger Domains (CHFR))

Autre désignation: Chfr,rnf196 (CHFR Produits)

Synonymes: RNF116 Protein, RNF196 Protein, CHFR Protein, fc43f10 Protein, si:dkey-69h6.7 Protein, wu:fc43f10 Protein, rnf116 Protein, rnf196 Protein, 5730484M20Rik Protein, C230082M18 Protein, checkpoint with forkhead and ring finger domains Protein, checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase Protein, checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase L homeolog Protein, CHFR Protein, chfr Protein, Chfr Protein, chfr.L Protein

Sujet: This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.

Poids moléculaire: 73.2 kDa

NCBI Accession: NP_001154816