HSD3B2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714232

Détail du produit

Antigène: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette HSD3B2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human 3-beta HSD2 / HSD3B2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Autre désignation: 3-beta Hsd2,hsd3b2 (HSD3B2 Produits)

Synonymes: HSD3B Protein, HSDB Protein, SDR11E2 Protein, Hsd3b1 Protein, 3b-HSD Protein, HSD3B1 Protein, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Protein, HSD3B2 Protein, Hsd3b2 Protein

Sujet: The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 41.9 kDa

NCBI Accession: NP_001159592

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis