ABHD12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714272

Détail du produit

Antigène: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ABHD12 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ABHD12 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Autre désignation: Abhd12 (ABHD12 Produits)

Synonymes: ABHD12 Protein, 1500011G07Rik Protein, 6330583M11Rik Protein, AI431047 Protein, AW547313 Protein, ABHD12A Protein, BEM46L2 Protein, C20orf22 Protein, PHARC Protein, dJ965G21.2 Protein, abhydrolase domain containing 12 Protein, abhydrolase domain containing 12 S homeolog Protein, ABHD12 Protein, CC1G_02966 Protein, PTRG_02160 Protein, abhd12.S Protein, Abhd12 Protein

Sujet: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011].

Poids moléculaire: 44.9 kDa

NCBI Accession: NP_001035937