EPS15 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714444

Détail du produit

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EPS15 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AF1P / EPS15 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))

Autre désignation: Af1p,eps15 (EPS15 Produits)

Synonymes: AF-1P Protein, AF1P Protein, MLLT5 Protein, CG16932 Protein, Dmel\\CG16932 Protein, EH1 Protein, EPS-15 Protein, Eps15 Protein, anon-WO0118547.85 Protein, eps-15 Protein, eps15 Protein, i31 Protein, 2410112D09Rik Protein, RGD1307641 Protein, epidermal growth factor receptor pathway substrate 15 Protein, Epidermal growth factor receptor pathway substrate clone 15 Protein, hypothetical protein Protein, EPS15 Protein, Eps-15 Protein, eps15 Protein, Eps15 Protein, PGTG_06574 Protein

Sujet: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 98.5 kDa

NCBI Accession: NP_001972

Pathways: EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation