ASIP Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714459

Détail du produit

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ASIP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Agouti-signaling protein (ASP) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Autre désignation: Agouti-Signaling Protein (Asp) (ASIP Produits)

Synonymes: AGSW Protein, AGTI Protein, AGTIL Protein, ASP Protein, SHEP9 Protein, ASIP Protein, AA960621 Protein, AI256638 Protein, D8Ertd580e Protein, PAR-3 Protein, Par3 Protein, Pard3a Protein, agouti signaling protein Protein, par-3 family cell polarity regulator Protein, ASIP Protein, Asip Protein, asip Protein, Pard3 Protein

Sujet: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Poids moléculaire: 12 kDa

NCBI Accession: NP_001663

Pathways: Cell-Cell Junction Organization, Feeding Behaviour