AGR2 Protein (His tag)

N° du produit ABIN2714465

Détail du produit

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette AGR2 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AGR2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Autre désignation: Agr2 (AGR2 Produits)

Synonymes: AG2 Protein, GOB-4 Protein, HAG-2 Protein, PDIA17 Protein, XAG-2 Protein, Agr2h Protein, Gob-4 Protein, mAG-2 Protein, wu:fj29g05 Protein, zgc:112187 Protein, agr2 Protein, hag3 Protein, hag-3 Protein, bcmp11 Protein, MGC89004 Protein, XAgr2 Protein, agr2-A Protein, anterior gradient 2, protein disulphide isomerase family member Protein, anterior gradient 2 Protein, anterior gradient 3, protein disulphide isomerase family member Protein, anterior gradient 2, protein disulphide isomerase family member S homeolog Protein, AGR2 Protein, Agr2 Protein, agr2 Protein, agr3 Protein, agr2.S Protein

Sujet: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.

Poids moléculaire: 18.9 kDa

NCBI Accession: NP_006399