AKR1D1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714509

Détail du produit

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette AKR1D1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AKR1D1 / SRD5B1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: AKR1D1 (Aldo-Keto Reductase Family 1, Member D1 (AKR1D1))

Autre désignation: Akr1d1,srd5b1 (AKR1D1 Produits)

Synonymes: 3o5bred Protein, CBAS2 Protein, SRD5B1 Protein, 3-oxo-5-beta-steroid 4-dehydrogenase-like Protein, aldo-keto reductase family 1 member D1 Protein, aldo-keto reductase family 1, member D1 Protein, aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) Protein, LOC491379 Protein, AKR1D1 Protein, Akr1d1 Protein

Sujet: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.

Poids moléculaire: 37.2 kDa

NCBI Accession: NP_005980

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process