AKTIP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714522

Détail du produit

Antigène: AKTIP (AKT Interacting Protein (AKTIP))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette AKTIP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AKTIP / FTS (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: AKTIP (AKT Interacting Protein (AKTIP))

Autre désignation: Aktip,fts (AKTIP Produits)

Synonymes: FT1 Protein, FTS Protein, cb798 Protein, fts Protein, zgc:77699 Protein, fts-A Protein, aktip Protein, fts-B Protein, MGC133931 Protein, AL023020 Protein, Fif Protein, Ft Protein, Ft1 Protein, Fts Protein, AKT interacting protein Protein, akt interacting protein Protein, AKT interacting protein L homeolog Protein, AKT interacting protein S homeolog Protein, thymoma viral proto-oncogene 1 interacting protein Protein, AKTIP Protein, aktip Protein, aktip.L Protein, aktip.S Protein, Aktip Protein

Sujet: The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

Poids moléculaire: 32.9 kDa

NCBI Accession: NP_071921