ATP2B4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715045

Détail du produit

Antigène: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ATP2B4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ATP2B4 / PMCA4 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Autre désignation: Atp2b4,pmca4 (ATP2B4 Produits)

Synonymes: ATP2B2 Protein, MXRA1 Protein, PMCA4 Protein, PMCA4b Protein, PMCA4x Protein, atp2b2 Protein, atp2b3 Protein, mxra1 Protein, pmca4 Protein, pmca4b Protein, pmca4x Protein, zgc:152801 Protein, ATP2B4 Protein, ATP2B1 Protein, Pmca4 Protein, ATPase plasma membrane Ca2+ transporting 4 Protein, ATPase, Ca++ transporting, plasma membrane 4 L homeolog Protein, ATPase, Ca++ transporting, plasma membrane 4 Protein, ATP2B4 Protein, atp2b4.L Protein, atp2b4 Protein, Atp2b4 Protein

Sujet: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 133.8 kDa

NCBI Accession: NP_001675

Pathways: Ribonucleoside Biosynthetic Process