B4GALT7 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2715127

Détail du produit

Antigène: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette B4GALT7 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human B4GALT7 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: B4GALT7 (Xylosylprotein beta 1,4-Galactosyltransferase, Polypeptide 7 (Galactosyltransferase I) (B4GALT7))

Autre désignation: b4galt7 (B4GALT7 Produits)

Synonymes: B4GAL-T7 Protein, EDSP1 Protein, XGALT1 Protein, XGPT1 Protein, beta-1,4-galactosyltransferase 7 Protein, xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) Protein, B4galt7 Protein, B4GALT7 Protein

Sujet: This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.

Poids moléculaire: 37.2 kDa

NCBI Accession: NP_009186

Pathways: Glycosaminoglycan Metabolic Process