DUSP11 Protein (His tag)

N° du produit ABIN2719826

Détail du produit

Antigène: DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette DUSP11 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DUSP11 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DUSP11 (Dual Specificity Phosphatase 11 (RNA/RNP Complex 1-Interacting) (DUSP11))

Autre désignation: Dusp11 (DUSP11 Produits)

Synonymes: pir1 Protein, DUSP11 Protein, 2010300F21Rik Protein, AI481497 Protein, wu:fa05e01 Protein, wu:fc09a06 Protein, wu:fk47e10 Protein, zgc:112166 Protein, PIR1 Protein, dusp11 Protein, dual specificity phosphatase 11 Protein, dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) Protein, dual specificity phosphatase 11 L homeolog Protein, DUSP11 Protein, DUSP11RC1I Protein, dusp11 Protein, Dusp11 Protein, dusp11.L Protein

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

Poids moléculaire: 38.8 kDa

NCBI Accession: NP_003575