EZH2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2720645

Détail du produit

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EZH2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human EZH2 / KMT6 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Pedram Fatemi, Salah-Uddin, Modarresi, Khoury, Wahlestedt, Faghihi: "Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen." dans: Journal of biomolecular screening, Vol. 20, Issue 9, pp. 1132-41, (2015) (PubMed).

Tushir, Akbarian: "Chromatin-bound RNA and the neurobiology of psychiatric disease." dans: Neuroscience, Vol. 264, pp. 131-41, (2014) (PubMed).

Détail du antigène

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: Ezh2,kmt6 (EZH2 Produits)

Synonymes: ENX-1 Protein, ENX1 Protein, EZH1 Protein, EZH2b Protein, KMT6 Protein, KMT6A Protein, WVS Protein, WVS2 Protein, eya2 Protein, im:7149338 Protein, zgc:136376 Protein, zgc:152758 Protein, EZH2 Protein, enx-1 Protein, enx1 Protein, ezh1 Protein, kmt6 Protein, xez Protein, Enx-1 Protein, Enx1h Protein, mKIAA4065 Protein, ezh2 Protein, olezh2 Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog Protein, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog Protein, EZH2 Protein, ezh2 Protein, Ezh2 Protein, ezh2.L Protein, ezh2.S Protein

Sujet: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 85.8 kDa

NCBI Accession: NP_004447

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation