TNNI2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2720884

Détail du produit

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TNNI2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Fast skeletal muscle Troponin I (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Autre désignation: Fast Skeletal Muscle Troponin I (TNNI2 Produits)

Synonymes: AMCD2B Protein, DA2B Protein, FSSV Protein, fsTnI Protein, TnI-F4 Protein, TnI Protein, TNI Protein, hm:zehn0173 Protein, tnni2 Protein, tropI-1d Protein, zgc:86800 Protein, troponin I2, fast skeletal type Protein, troponin I type 2 (skeletal, fast) Protein, troponin I, fast skeletal muscle-like Protein, troponin I, skeletal, fast 2 Protein, troponin I type 2a (skeletal, fast), tandem duplicate 4 Protein, TNNI2 Protein, Tnni2 Protein, tnni2a.4 Protein

Sujet: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 21.2 kDa

NCBI Accession: NP_003273