FNIP2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721270

Détail du produit

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FNIP2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human FNIP2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: FNIP2 (Folliculin Interacting Protein 2 (FNIP2))

Autre désignation: Fnip2 (FNIP2 Produits)

Synonymes: LOC797213 Protein, FNIPL Protein, MAPO1 Protein, D630023B12Rik Protein, mKIAA1450 Protein, RGD1562174 Protein, folliculin interacting protein 2 Protein, si:ch211-42i9.8 Protein, FNIP2 Protein, si:ch211-42i9.8 Protein, fnip2 Protein, Fnip2 Protein

Sujet: This gene encodes a member of the folliculin-interacting protein family. The encoded protein binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK) and be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This protein may also play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. A homologous binding partner of this protein, folliculin-interacting protein 1, has similar binding activities and may suggest functional redundancy within this protein family. Both folliculin-interacting proteins have also been shown to bind the molecular chaperone heat shock protein-90 (Hsp90) and they may function as a co-chaperones in the stabilization of tumor suppressor folliculin which is a target of Hsp90 chaperone activity.

Poids moléculaire: 121.9 kDa

NCBI Accession: NP_065891