FOXP3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2721384

Détail du produit

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FOXP3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human FOXP3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Larsen, Munir, Woetmann, Frøsig, Odum, Svane, Becker, Andersen: "Functional characterization of Foxp3-specific spontaneous immune responses." dans: Leukemia, Vol. 27, Issue 12, pp. 2332-40, (2013) (PubMed).

Détail du antigène

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Autre désignation: Foxp3 (FOXP3 Produits)

Synonymes: foxp3 Protein, FOXP3 Protein, AIID Protein, DIETER Protein, IPEX Protein, PIDX Protein, XPID Protein, JM2 Protein, scurfin Protein, sf Protein, RGD1562112 Protein, forkhead box P3 Protein, forkhead box P3a Protein, forkhead box P3 L homeolog Protein, FOXP3 Protein, foxp3a Protein, foxp3 Protein, foxp3.L Protein, Foxp3 Protein

Sujet: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 47.1 kDa

NCBI Accession: NP_054728

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation