GNA11 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721492

Détail du produit

Antigène: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GNA11 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human G protein alpha 11 / GNA11 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Autre désignation: G Protein alpha 11,gna11 (GNA11 Produits)

Synonymes: Dsk7 Protein, E430025L19 Protein, GNA-11 Protein, HHC2 Protein, HYPOC2 Protein, G-alpha-11 Protein, gna11 Protein, si:dkey-42p8.2 Protein, wu:fb12d06 Protein, zgc:101761 Protein, guanine nucleotide binding protein, alpha 11 Protein, G protein subunit alpha 11 Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) Protein, guanine nucleotide regulatory protein G11 alpha subunit Protein, guanine nucleotide binding protein (G protein), alpha 11a (Gq class) Protein, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) S homeolog Protein, guanine nucleotide binding protein (G protein), alpha 11b (Gq class) Protein, Gna11 Protein, GNA11 Protein, gna11 Protein, gna11a Protein, gna11.S Protein, gna11b Protein

Sujet: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Poids moléculaire: 41.9 kDa

NCBI Accession: NP_002058

Pathways: G-protein mediated Events