GADD45GIP1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721585

Détail du produit

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GADD45GIP1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GADD45GIP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Autre désignation: Gadd45gip1 (GADD45GIP1 Produits)

Synonymes: si:dkey-194e13.6 Protein, CKBBP2 Protein, CRIF1 Protein, PLINP Protein, PLINP-1 Protein, PRG6 Protein, Plinp1 Protein, 2310040G17Rik Protein, AI425883 Protein, Crif1 Protein, growth arrest and DNA-damage-inducible, gamma interacting protein 1 Protein, GADD45G interacting protein 1 Protein, gadd45gip1 Protein, GADD45GIP1 Protein, Gadd45gip1 Protein

Sujet: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 25.2 kDa

NCBI Accession: NP_443082