GALE Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2721597

Détail du produit

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GALE protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GALE (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Autre désignation: Gale (GALE Produits)

Synonymes: GALE Protein, im:7147391 Protein, wu:fb05f01 Protein, zgc:136578 Protein, F15H21.11 Protein, F15H21_11 Protein, REB1 Protein, ROOT EPIDERMAL BULGER1 Protein, ROOT HAIR DEFECTIVE 1 Protein, UDP-GLUCOSE 4-EPIMERASE Protein, UGE4 Protein, ECK0748 Protein, galD Protein, JW0742 Protein, SMU.888 Protein, BA5505 Protein, BA5700 Protein, VFA0352 Protein, galE Protein, 2310002A12Rik Protein, AI323962 Protein, 1n569 Protein, xgale Protein, SDR1E1 Protein, UDP-galactose-4-epimerase Protein, NAD(P)-binding Rossmann-fold superfamily protein Protein, UDP-galactose 4-epimerase GalE Protein, UDP-glucose 4-epimerase Protein, UDP-glucose 4-epimerase GalE Protein, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase Protein, galactose-4-epimerase, UDP Protein, UDP-galactose-4-epimerase L homeolog Protein, GALE Protein, gale Protein, RHD1 Protein, ECs0787 Protein, galE Protein, galE1 Protein, galE2 Protein, STY0809 Protein, galE-2 Protein, SG0897 Protein, galD Protein, Ent638_1250 Protein, Gale Protein, gale.L Protein

Sujet: This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild (&aposperipheral&apos form) to severe (&aposgeneralized&apos form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

Poids moléculaire: 38.1 kDa

NCBI Accession: NP_001008217

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process