GATA4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721732

Détail du produit

Antigène: GATA4 (GATA Binding Protein 4 (GATA4))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GATA4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human GATA4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Biological Activity Comment: GATA4 Activity Verified in a DNA-binding Assay: Comparison of GATA4 binding to consensus and mutant oligos shows sensitivity of protein binding to the DNA sequence used.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: > 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GATA4 (GATA Binding Protein 4 (GATA4))

Autre désignation: Gata4 (GATA4 Produits)

Synonymes: gata-4 Protein, xgata4 Protein, xGATA-4 Protein, MGC81427 Protein, GATA4 Protein, GATA-4 Protein, Gata4 Protein, gata4 Protein, ASD2 Protein, VSD1 Protein, Gata-4 Protein, gata Protein, GATA binding protein 4 Protein, GATA binding protein 4 L homeolog Protein, glutamyl-tRNA(Gln) amidotransferase subunit A Protein, gata4 transcription factor Protein, GATA binding protein 4 S homeolog Protein, GATA4 Protein, gata4.L Protein, gata4 Protein, gatA4 Protein, Gata4 Protein, gata4.S Protein

Sujet: This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 44.4 kDa

NCBI Accession: NP_002043

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis