GEMIN5 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721790

Détail du produit

Antigène: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GEMIN5 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Gemin-5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Francisco-Velilla, Fernandez-Chamorro, Ramajo, Martinez-Salas: "The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation." dans: Nucleic acids research, Vol. 44, Issue 17, pp. 8335-51, (2016) (PubMed).

Détail du antigène

Antigène: GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))

Autre désignation: Gemin-5 (GEMIN5 Produits)

Synonymes: GEMIN-5 Protein, AA407055 Protein, AA407208 Protein, AI451603 Protein, BB194447 Protein, C330013N08 Protein, gem nuclear organelle associated protein 5 Protein, gem (nuclear organelle) associated protein 5 Protein, GEMIN5 Protein, Gemin5 Protein

Sujet: This gene encodes a WD repeat protein that is a component of the survival of motor neurons (SMN) complex. The SMN complex plays a critical role in mRNA splicing through the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs), and may also mediate the assembly and transport of other classes of ribonucleoproteins. The encoded protein is the snRNA-binding component of the SMN complex. Dysregulation of this gene may play a role in alternative mRNA splicing and tumor cell motility. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Poids moléculaire: 168.4 kDa

NCBI Accession: NP_056280

Pathways: Ribonucleoprotein Complex Subunit Organization