GCNT2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2721960

Détail du produit

Antigène: GCNT2 (Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GCNT2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (GCNT2), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GCNT2 (Glucosaminyl (N-Acetyl) Transferase 2, I-Branching Enzyme (I Blood Group) (GCNT2))

Abstract: GCNT2 Produits

Synonymes: 5330430K10Rik Protein, IGnT Protein, IGnTA Protein, IGnTB Protein, IGnTC Protein, Ignt Protein, CCAT Protein, CTRCT13 Protein, GCNT2C Protein, GCNT5 Protein, IGNT Protein, II Protein, NACGT1 Protein, NAGCT1 Protein, ULG3 Protein, bA360O19.2 Protein, bA421M1.1 Protein, glucosaminyl (N-acetyl) transferase 2, I-branching enzyme Protein, glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) Protein, Gcnt2 Protein, GCNT2 Protein

Sujet: This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 46.4 kDa

NCBI Accession: NP_663630

Pathways: Glycosaminoglycan Metabolic Process