Glutathione S-Transferase alpha 3 (GSTA3) protein (Myc-DYKDDDDK Tag) Protein
GSTA3 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2722270
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- Nom de la protéine
- Type de proteíne
- HEK-293 Cells
- Myc-DYKDDDDK Tag
- Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
- Optimal preservation of protein structure, post-translational modifications and functions.
- Attributs du produit
- Recombinant human GSTA3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Indications d'application
- Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
In vitro biochemical assays and cell-based functional assays
The tag is located at the C-terminal.
- For Research Use only
- > 50 μg/mL
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
- Nom de la protéine
- GSTA3, GST, GSTA1, GSTA3-3, GTA3, GSTA2, Gst2-3, Yc2, glutathione S-transferase alpha 3, glutathione S-transferase A2, glutathione S-transferase, glutathione S-transferase, alpha 3, glutathione S-transferase Yc, GSTA3, LOC474938, gsta3, Gsta3, LOC100328911
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
- Poids moléculaire
- 25.1 kDa
- NCBI Accession
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