UBE2K Protein (Transcript Variant 3) (His tag)

N° du produit ABIN2722759

Détail du produit

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBE2K protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human HIP2 / UBE2K (transcript variant 3) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Autre désignation: Hip2,ube2k (UBE2K Produits)

Synonymes: E2-25K Protein, HIP2 Protein, HYPG Protein, LIG Protein, UBC1 Protein, E2-25k Protein, Hip2 Protein, Hypg Protein, Lig Protein, e2-25k Protein, hip2 Protein, hypg Protein, lig Protein, AW492011 Protein, D5Ertd601e Protein, ube2k Protein, zgc:103472 Protein, zgc:110791 Protein, ubiquitin conjugating enzyme E2 K Protein, ubiquitin-conjugating enzyme E2K Protein, ubiquitin conjugating enzyme E2 K S homeolog Protein, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Protein, UBE2K Protein, Ube2k Protein, ube2k.S Protein, ube2k Protein, ube2kb Protein, ube2ka Protein

Sujet: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Poids moléculaire: 48.7 kDa

NCBI Accession: NP_001104583