HNRNPA1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722904

Détail du produit

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette HNRNPA1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human hnRNP core protein A1 / HNRNPA1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Zheng, Worthington, Timms, Woo: "HNRNPA1 interacts with a 5'-flanking distal element of interleukin-6 and upregulates its basal transcription." dans: Genes and immunity, Vol. 14, Issue 8, pp. 479-86, (2013) (PubMed).

Détail du antigène

Antigène: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Autre désignation: Hnrnp Core Protein a1,hnrnpa1 (HNRNPA1 Produits)

Synonymes: HNRPA1 Protein, HNRPA1L3 Protein, hnRNP A1 Protein, hnRNP-A1 Protein, hnrpa1 Protein, TPT1P Protein, HNRNPA1 Protein, D15Ertd119e Protein, Hdp Protein, Hnrpa1 Protein, hnrnp-A1 Protein, ROA1 Protein, zgc:66127 Protein, heterogeneous nuclear ribonucleoprotein A1 Protein, heterogeneous nuclear ribonucleoprotein A1b Protein, Heterogeneous nuclear ribonucleoprotein A1 Protein, heterogeneous nuclear ribonucleoprotein A1 S homeolog Protein, ribonucleoprotein A1a Protein, heterogeneous nuclear ribonucleoprotein A1-like Protein, heterogeneous nuclear ribonucleoprotein A1a Protein, HNRNPA1 Protein, hnrnpa1b Protein, LOC100101226 Protein, roa1 Protein, Hnrnpa1 Protein, hnrnpa1.S Protein, hnrnpa1 Protein, LOC100359118 Protein, hnrnpa1a Protein

Sujet: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Poids moléculaire: 34 kDa

NCBI Accession: NP_002127