IDUA Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723286

Détail du produit

Antigène: IDUA (Iduronidase, alpha-L- (IDUA))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IDUA protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Alpha-L-iduronidase / IDUA protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IDUA (Iduronidase, alpha-L- (IDUA))

Autre désignation: Iduronidase, alpha-L (Idua) (IDUA Produits)

Synonymes: IDA Protein, MPS1 Protein, 6030426D08 Protein, alpha-L-iduronidase Protein, MGC80842 Protein, si:ch211-12e13.9 Protein, IDUA Protein, iduronidase, alpha-L- Protein, iduronidase, alpha-L- L homeolog Protein, alpha-L-iduronidase Protein, IDUA Protein, Idua Protein, idua.L Protein, idua Protein, LOC5564727 Protein

Sujet: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Poids moléculaire: 70 kDa

NCBI Accession: NP_000194

Pathways: Glycosaminoglycan Metabolic Process