ILF2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723410

Détail du produit

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ILF2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ILF2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Autre désignation: Ilf2 (ILF2 Produits)

Synonymes: nf45 Protein, pro3063 Protein, ILF2 Protein, wu:fb34h01 Protein, zgc:73084 Protein, zgc:77276 Protein, NF45 Protein, PRO3063 Protein, 6230405A16Rik Protein, TEG-267 Protein, Tex261 Protein, Tex267 Protein, interleukin enhancer binding factor 2 Protein, interleukin enhancer binding factor 2 L homeolog Protein, ilf2 Protein, ILF2 Protein, ilf2.L Protein, Ilf2 Protein

Sujet: The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

Poids moléculaire: 42.9 kDa

NCBI Accession: NP_004506