INPP5E Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723486

Détail du produit

Antigène: INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette INPP5E protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human INPP5E protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: INPP5E (Inositol Polyphosphate-5-Phosphatase, 72 KDa (INPP5E))

Autre désignation: Inpp5e (INPP5E Produits)

Synonymes: 1200002L24Rik Protein, 72kDa Protein, mKIAA0123 Protein, CORS1 Protein, CPD4 Protein, JBTS1 Protein, MORMS Protein, PPI5PIV Protein, PMPCA Protein, inositol polyphosphate-5-phosphatase E Protein, Inpp5e Protein, INPP5E Protein

Sujet: The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. Mutations in this gene cause Joubert syndrome a clinically and genetically heterogenous group of disorders characterized by midbrain-hindbrain malformation and various associated ciliopathies that include retinal dystrophy, nephronophthisis, liver fibrosis and polydactyly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 70 kDa

NCBI Accession: NP_063945