IL-24 Protein (Transcript Variant 1) (His tag)

N° du produit ABIN2723686

Détail du produit

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: CHO Cells

Purification/Conjugué: Cette IL-24 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Interleukin-24 / IL24 (transcript variant 1) protein expressed in CHO cells.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: Interleukin-24,il24 (IL24 Produits)

Synonymes: C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein

Sujet: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 18.9 kDa

NCBI Accession: NP_006841

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy