KCNJ6 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2724044

Détail du produit

Antigène: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette KCNJ6 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human KCNJ6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: KCNJ6 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 6 (KCNJ6))

Autre désignation: Kcnj6 (KCNJ6 Produits)

Synonymes: kcnj6 Protein, BIR1 Protein, GIRK-2 Protein, GIRK2 Protein, KATP-2 Protein, KATP2 Protein, KCNJ7 Protein, KIR3.2 Protein, hiGIRK2 Protein, Kir3.2 Protein, weaver Protein, wv Protein, potassium voltage-gated channel subfamily J member 6 Protein, potassium channel, inwardly rectifying subfamily J, member 5 Protein, potassium inwardly-rectifying channel, subfamily J, member 6 Protein, KCNJ6 Protein, kcnj5 Protein, Kcnj6 Protein

Sujet: This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 48.3 kDa

NCBI Accession: NP_002231