Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2724964

Détail du produit

Antigène: Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Myc-DYKDDDDK Tag

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LRTOMT / LRRC51 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)

Autre désignation: Lrtomt,lrrc51 (LRTOMT Produits)

Synonymes: DFNB63 Protein, LRRC51 Protein, Lrtomt Protein, RGD1561509 Protein, lrrp51 Protein, lrtomt Protein, zgc:153736 Protein, leucine rich transmembrane and O-methyltransferase domain containing Protein, leucine-rich repeat-containing protein 51 Protein, leucine rich repeat containing 51 Protein, LRTOMT Protein, LRRC51 Protein, Lrtomt Protein, lrrc51 Protein

Sujet: This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene.

Poids moléculaire: 22 kDa

NCBI Accession: NP_660352

Pathways: Sensory Perception of Sound