LRWD1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2724965

Détail du produit

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LRWD1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LRWD1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Autre désignation: Lrwd1 (LRWD1 Produits)

Synonymes: CENP-33 Protein, ORCA Protein, 1200011O22Rik Protein, AU042569 Protein, AW548074 Protein, Orca Protein, si:dkey-261j4.9 Protein, wu:fb78b03 Protein, wu:ft31b04 Protein, leucine rich repeats and WD repeat domain containing 1 Protein, leucine-rich repeats and WD repeat domain containing 1 Protein, microRNA 5090 Protein, leucine-rich repeats and WD repeat domain containing 1 L homeolog Protein, LRWD1 Protein, Lrwd1 Protein, lrwd1 Protein, MIR5090 Protein, lrwd1.L Protein

Sujet: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 70.7 kDa

NCBI Accession: NP_690852

Pathways: Chromatin Binding