LZTFL1 Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour LZTFL1 Protein (Myc-DYKDDDDK Tag) (ABIN2725086)
Antigène
Voir toutes LZTFL1 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette LZTFL1 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human LZTFL1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))
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Autre désignation
- Lztfl1
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Sujet
- This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants.
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Poids moléculaire
- 34.4 kDa
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NCBI Accession
- NP_065080
Antigène
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