LZTS1 Protein (His tag)

N° du produit ABIN2725087

Détail du produit

Antigène: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LZTS1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LZTS1 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Autre désignation: Lzts1 (LZTS1 Produits)

Synonymes: F37 Protein, FEZ1 Protein, Psdzip70 Protein, LZTS1 Protein, f37 Protein, fez1 Protein, leucine zipper tumor suppressor 1 Protein, leucine zipper, putative tumor suppressor 1 Protein, LZTS1 Protein, Lzts1 Protein, lzts1 Protein

Sujet: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Poids moléculaire: 66.4 kDa

NCBI Accession: NP_066300

Pathways: Synaptic Membrane