MARCH2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725492

Détail du produit

Antigène: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MARCH2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MARCH2 / RNF172 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MARCH2 (Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase (MARCH2))

Autre désignation: March2,rnf172 (MARCH2 Produits)

Synonymes: MARCH-II Protein, RNF172 Protein, rgd1306395 Protein, marh2 Protein, RGD1306395 Protein, 9530046H09Rik Protein, membrane associated ring-CH-type finger 2 Protein, membrane associated ring-CH-type finger 2 S homeolog Protein, E3 ubiquitin-protein ligase MARCH2 Protein, membrane-associated ring finger (C3HC4) 2 Protein, MARCH2 Protein, march2.S Protein, march2 Protein, Tsp_09446 Protein, marh2 Protein, March2 Protein

Sujet: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266] Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]

Poids moléculaire: 26.8 kDa

NCBI Accession: NP_001005415