MARCH8 Protein (Transcript Variant 8) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725495

Détail du produit

Antigène: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 8

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MARCH8 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MARCH8 (transcript variant 8) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MARCH8 (Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8))

Autre désignation: March8 (MARCH8 Produits)

Synonymes: MARCH-VIII Protein, MIR Protein, RNF178 Protein, c-MIR Protein, zgc:171495 Protein, 1300017E09Rik Protein, Mir Protein, Mar-08 Protein, MARCH8 Protein, membrane associated ring-CH-type finger 8 Protein, membrane-associated ring finger (C3HC4) 8 Protein, membrane associated ring-CH-type finger 8 L homeolog Protein, MARCH8 Protein, march8 Protein, March8 Protein, march8.L Protein

Sujet: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153] Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]

Poids moléculaire: 32.8 kDa

NCBI Accession: NP_659458