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MBP Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

MBP Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2726638
  • Antigène Voir toutes MBP Protéines
    MBP (Myelin Basic Protein (MBP))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 11
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 13
    • 13
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette MBP protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Myelin Basic Protein (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MBP Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    MBP (Myelin Basic Protein (MBP))
    Autre désignation
    Myelin Basic Protein (MBP Produits)
    Synonymes
    C76307 Protein, Hmbpr Protein, R75289 Protein, golli-mbp Protein, mld Protein, shi Protein, Mbps Protein, cb274 Protein, fj33b11 Protein, mbp Protein, wu:fj33b11 Protein, wu:fq15b02 Protein, zgc:136630 Protein, MGC115135 Protein, myelin basic protein Protein, myelin basic protein a Protein, myelin basic protein L homeolog Protein, MBP Protein, Mbp Protein, mbpa Protein, mbp Protein, mbp.L Protein
    Sujet
    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
    Poids moléculaire
    18.4 kDa
    NCBI Accession
    NP_001020261
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