NECAB3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2727054

Détail du produit

Antigène: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NECAB3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NECAB3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Autre désignation: Necab3 (NECAB3 Produits)

Synonymes: Apba2bp Protein, APBA2BP Protein, NECAB3 Protein, EFCBP3 Protein, NIP1 Protein, STIP3 Protein, SYTIP2 Protein, XB51 Protein, dJ63M2.4 Protein, dJ63M2.5 Protein, 2900010M17Rik Protein, AI853434 Protein, Nip1 Protein, N-terminal EF-hand calcium binding protein 3 Protein, Necab3 Protein, NECAB3 Protein

Sujet: The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 40.6 kDa

NCBI Accession: NP_112508