NKX2-8 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2727355

Détail du produit

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NKX2-8 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NKX2-8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: Nkx2-8 (NKX2-8 Produits)

Synonymes: NKX2.8 Protein, NKX2H Protein, Nkx2-9 Protein, Nkx-2.9 Protein, Nkx2-8 Protein, Nkx2.9 Protein, tinman Protein, NK2 homeobox 8 Protein, NK2 homeobox 9 Protein, NKX2-8 Protein, Nkx2-9 Protein, Nkx2-8 Protein

Sujet: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Poids moléculaire: 25.7 kDa

NCBI Accession: NP_055175