NR1H2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2727542

Détail du produit

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette NR1H2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NR1H2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Autre désignation: Nr1h2 (NR1H2 Produits)

Synonymes: NR1H2 Protein, lxr-b Protein, lxrb Protein, ner Protein, ner-i Protein, rip15 Protein, unr Protein, DKFZp468A0622 Protein, AI194859 Protein, LXR Protein, LXRB Protein, LXRbeta Protein, NER1 Protein, OR-1 Protein, RIP15 Protein, UR Protein, Unr Protein, Unr2 Protein, LXR-b Protein, NER Protein, NER-I Protein, UNR Protein, nuclear receptor subfamily 1 group H member 2 Protein, nuclear receptor subfamily 1, group H, member 2 Protein, nuclear receptor subfamily 1 group H member 2 L homeolog Protein, NR1H2 Protein, nr1h2 Protein, Nr1h2 Protein, nr1h2.L Protein

Sujet: The liver X receptors, LXRA (NR1H3 MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].

Poids moléculaire: 50.9 kDa

NCBI Accession: NP_009052

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding