NSMCE2 Protein (His tag)

N° du produit ABIN2727651

Détail du produit

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NSMCE2 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human NSMCE2 (full length, N-term HIS tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Autre désignation: Nsmce2 (NSMCE2 Produits)

Synonymes: 1110014D18Rik Protein, AI661537 Protein, RGD1305156 Protein, C8orf36 Protein, MMS21 Protein, NSE2 Protein, ZMIZ7 Protein, Non-SMC element 2 Protein, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase Protein, NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog Protein, Smc5-6 complex non-SMC subunit 2 Protein, Nsmce2 Protein, NSMCE2 Protein, nsmce2.L Protein, nse2 Protein

Sujet: This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.

Poids moléculaire: 27.8 kDa

NCBI Accession: NP_775956