OPTN Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2727924

Détail du produit

Antigène: OPTN (Optineurin (OPTN))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette OPTN protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Optineurin / HIP7 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: OPTN (Optineurin (OPTN))

Autre désignation: Optineurin,hip7 (OPTN Produits)

Synonymes: nrp Protein, fip2 Protein, hip7 Protein, hypl Protein, glc1e Protein, tfiiia-intp Protein, ALS12 Protein, FIP2 Protein, GLC1E Protein, HIP7 Protein, HYPL Protein, NRP Protein, TFIIIA-INTP Protein, Fip2 Protein, 4930441O07Rik Protein, fj52f04 Protein, si:ch211-240l19.3 Protein, wu:fj52f04 Protein, zgc:66386 Protein, zgc:77868 Protein, optineurin Protein, optineurin L homeolog Protein, OPTN Protein, optn Protein, Optn Protein, optn.L Protein

Sujet: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Poids moléculaire: 65.7 kDa

NCBI Accession: NP_001008212

Pathways: M Phase