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PDE11A Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

PDE11A Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2728475
  • Antigène Voir toutes PDE11A Protéines
    PDE11A (phosphodiesterase 11A (PDE11A))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 4
    Origine
    • 2
    • 2
    • 1
    Humain
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PDE11A protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human PDE11A (transcript variant 4) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PDE11A Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PDE11A (phosphodiesterase 11A (PDE11A))
    Autre désignation
    Pde11a (PDE11A Produits)
    Synonymes
    PPNAD2 Protein, 6330414F14Rik Protein, A630086N24Rik Protein, Gm350 Protein, PDE11A1 Protein, si:ch211-222f23.5 Protein, PDE11A Protein, ppnad2 Protein, Pde11a Protein, phosphodiesterase 11A Protein, phosphodiesterase 11a Protein, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Protein, PDE11A Protein, Pde11a Protein, pde11a Protein, LOC100470038 Protein
    Sujet
    The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    104.6 kDa
    NCBI Accession
    NP_058649
    Pathways
    cAMP Metabolic Process
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